This Book Constitutes The Thoroughly Refereed Post-conference Proceedings Of The Second International Conference On Swarm Intelligence Based Optimization, Icsibo 2016, Held In Mulhouse, France, In June 2016.the 9 Full Papers Presented Were Carefully Reviewed And Selected From 20 Submissions. They Are Centered Around The Following Topics: Theoretical Advances Of Swarm Intelligence Metaheuristics; Combinatorial Discrete, Binary, Constrained, Multi-objective, Multi-modal, Dynamic, Noisy, And Large Scale Optimization; Artificial Immune Systems, Particle Swarms, Ant Colony, Bacterial Forging, Artificial Bees, Fireflies Algorithm; Hybridization Of Algorithms; Paralleldistributed Computing, Machine Learning, Data Mining, Data Clustering, Decision Making And Multi-agent Systems Based On Swarm Intelligence Principles; Adaptation And Applications Of Swarm Intelligence Principles To Real World Problems In Various Domains.