1 2?3?-Cyclic Nucleotide 3?-Phosphodiesterase. - 1. Introduction. - 2. Assay of CNPase. - 3. Association of CNPase with Myelin. - 4. CNPase in Nonmyelin Fractions. - 5. Activation and Isolation. - 6. Properties. - 7. CNPase in Pathological Conditions. - 8. Conclusions and Speculations. - 9. References. - 2 Immunohistochemistry of Nervous System-Specific Antigens. - 1. Introduction. - 2 Immunofluorescent Markers. - 3. Heavy Metal Markers. - 4. Enzyme Markers. - 5. Multiple Antigen Localization. - 6. Tissue Preparation. - 7. Immunohistologic Controls. - 8. General Immunohistochemical Application. - 9. Nervous System Antigens. - 10. References. - 3 Molecular Composition and Functional Organization of Synaptic Structures. - 1. Introduction. - 2. Preparation of Synaptic Structures. - 3. Characterization of Synaptic Structures. - 4. Functional Organization. - 5. Prospect. - 6. References. - 4 The Multiple Roles of Glutamate and Aspartate in Neural Tissues. - 1. Introduction. - 2. The Putative Neurotransmitter Function. - 3. Glutamate and Aspartate as Constituents of Protein. - 4. The Role in the Regulation and Maintenance of Intracellular Osmotic and Ionic Balance. - 5. The Roles of Glutamate and Aspartate in Nitrogen Metabolism. - 6. The Involvement of Glutamate and Aspartate in Energy Metabolism. - 7. Compounds of Neurochemical Interest Derived from Glutamate and Aspartate. - 8. The Possible Role of Glutamate in Amino Acid Transport. - 9. Future Directions. - 10. References. - 5 Biochemical Aspects of Transmission at Inhibitory Synapses: The Role of Glycine. - 1. Introduction. - 2. The Presynaptic Criterion. - 3. The Criterion of Identity of Action. - 4. The Release Criterion. - 5. Other Neurobiological Supportive Studies. - 6. Metabolic Studies. - 7. Other Experimental Studies. - 8. A Functional Model ofGlycinergic Neurotransmission. - 9. Neurological Significance. - 10. Concluding Remarks. - 11. References. Language: English